HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxy-3-(1-methylethoxy)benzo[b]thiophene-2-carboxylic acid → HCID 18961220, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxy-3-(1-methylethoxy)benzo[b]thiophene-2-carboxylic acid | HCID 13961648 | — |
| Reactant | HCID 18961215 | HCID 18961215 | — |
| Product | HCID 18961220 | HCID 18961220 | 56% |
Reaction Steps
Following a procedure analogous to Example 12, 5-methoxy-3-(1-methylethoxy)benzo[b]thiophene-2-carboxylic acid (300 mg, 1.1 mmol) and 402 mg, 1.8 mmol) methyl 4-aminobenzenesulfonate [obtained by catalytic hydrogenation of methyl 4-nitrobenzenesulfonate (Aldrich) followed by salt formation] provides 295 mg (56%) of product; mp 176.5°-177° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05356926 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-b93bee7452ac4b888fb1c0db9bed6e6d |
| Source note | uspto-grants-1994_10 |