HCID 18961261, compound → HCID 18961264, compound

Participants

Reaction Steps

A mixture of 5.0 g (11.8 mmol) of 5,7-di-tert-butyl-3-(4-ethoxycarbonylmethoxyphenyl)benzofuran-2-one (Compound (113), Example 6) and 2 g of strong acidic ion exchanger (Dowex) in 50 ml of methanol is refluxed for 4 hours. The reaction mixture is filtered, and the filtrate is concentrated on a vacuum rotary evaporator. Crystallisation of the residue from ligroin gives 3.0 g (62%) of 5,7-di-tert-butyl-3-(4-methoxycarbonylmethoxyphenyl)benzofuran-2-one, melting point 115°-117° C. (Compound 115), Table 1).

Provenance & Evidence