2-Methyl-2-butene → HCID 18958832, compound

HRID 1708422Notes

Reaction equation

HRID 1708422 reaction equation
[ClH:1].CO[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[C:17]2[O:18][CH2:19][C:20]([CH3:23])([CH3:22])[N:21]=2)=[CH:7][CH:6]=1.CC=C(C)C.B(Br)(Br)[Br:30]>C(Cl)(Cl)Cl>[ClH:1].[Br:30][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[C:17]2[O:18][CH2:19][C:20]([CH3:23])([CH3:22])[N:21]=2)=[CH:7][CH:6]=1

Participants

5

Reactant 3

HCID 105532-Methyl-2-buteneHCID 25134Boron tribromideHCID 18958868HCID 18958868, compound

Product 1

HCID 18958832HCID 18958832, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Conditions

Temperature
0 °C

Procedure

5 g of 4'-methoxymethyl-2-(4,4-dimethyl-2-oxazolinyl)biphenyl hydrochloride, prepared in B/, are dissolved in 75 ml of chloroform stabilised with amylene, and 3.2 ml of boron tribromide are added while cooling to 0° C. The mixture is stirred for one hour at 0° C. and washed with cold water. The organic phase is separated after settling has taken place, then dried over magnesium sulphate and evaporated under vacuum to give 5.2 g of 4'-bromomethyl-2-(4,4-dimethyl-2-oxazolinyl)biphenyl hydrochloride in the form of crystals of melting point 126°-127° C.

Workup

  1. additionare added
  2. washwashed with cold water
  3. customThe organic phase is separated after settling
  4. dry with materialdried over magnesium sulphate
  5. customevaporated under vacuum

Sources & evidence

ORD record
ord-86e069974e774e698a63fb014ab98fec
Source dataset
uspto-grants-1994_10
Patent number
US05358950

Reaction notes

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