反应详情

A solution of 800 mg of the product of Example 7 in 100 ml of acetone containing 3 drops of 5% HC1 is refluxed for 16 hours. The reaction mixture is concentrated in vacuo to a residue which is purified by column chromatography on silica gel by elution with 70% ethyl acetate-hexanes to give 350 mg of the desired product as a solid. M+H 503

1. concentrationThe reaction mixture is concentrated in vacuo to a residue which
2. customis purified by column chromatography on silica gel by elution with 70% ethyl acetate-hexanes