HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-dihydro-2H-pyran → 2H-Pyran, 2-[(12-bromododecyl)oxy]tetrahydro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| Reactant | 12-Bromo-1-dodecanol | HCID 137895 | — |
| Reactant | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2H-Pyran, 2-[(12-bromododecyl)oxy]tetrahydro- | HCID 11078592 | — |
Reaction Steps
To a solution of 12-bromo-1-dodecanol (1 mole) in dichloromethane containing pyridinium p-toluenesulfonate (P-TSA) is added dihydropyran (2 moles). The reaction mixture is stirred for 24 hours and then washed twice with water and dried over anhydrous MgSO4. The dichloromethane is removed under reduced pressure. If necessary the resulting product is purified by chromatography on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05359030 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-da39796a29174254b096a01c090bc639 |
| Source note | uspto-grants-1994_10 |