HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → N,N-Dimethyl-1H-imidazole-1-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Dimethylsulphamoyl chloride | HCID 83372 | — |
| Product | N,N-Dimethyl-1H-imidazole-1-sulfonamide | HCID 395751 | — |
Reaction Steps
Imidazole was treated with dimethyl amino sulfonyl chloride providing 1-(dimethylaminosulfonyl)-imidazole, which was subsequently treated with n-butyl lithium and t-butyldimethylsilyl chloride to afford 1-(dimethylaminosulfonyl)-2-(t-butyldimethylsilyl)-imidazol e. This material was treated with n-butyllithium and tri-n-butyltin chloride to afford the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05359051 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-ad631ce524fd45f4aa207552e089d1ca |
| Source note | uspto-grants-1994_10 |