Sodium borohydride → HCID 18958967, compound

Participants

Reaction Steps

This was prepared as described in Example 10 by sodium borohydride reduction of 4-(8-chloro-5,6-dihydro-5-oxo-11H-benzo[5,6]cyclohepta[1,2-b]pyrid-11-ylidene)-1-[4-(2-methyimidazo[4,5-c]pyrid-1-yl)benzoyl]piperidine (from Example 18; 40 mg). The title compound was obtained as a yellow foam (35 mg, 87%) which was characterised as a hydrate containing 0.33 equivalents of ethyl acetate. Found: C,67.7; H,5.2; N,11.4. C33H28ClN5O2. H2O. 0.33 C4H8O2 requires C,67.7; H,5.1; N,11.5%.

Provenance & Evidence