HuagongsheHuagongshe Chemistry Print Report · For research reference only
20-(5,5-Dimethyl-1,3-dioxan-2-yl)pregna-1,4,6-trien-3-one → 20-(1,3-Dioxolan-2-yl)-1alpha,2alpha-epoxypregna-4,6-dien-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 20-(5,5-Dimethyl-1,3-dioxan-2-yl)pregna-1,4,6-trien-3-one | HCID 22843932 | — |
| Reactant | 20-(1,3-Dioxolan-2-yl)pregna-1,4,6-trien-3-one | HCID 54063702 | — |
| Product | 20-(1,3-Dioxolan-2-yl)-1alpha,2alpha-epoxypregna-4,6-dien-3-one | HCID 86745815 | 75% |
Reaction Steps
The procedure of Example 6 was repeated except that 4.16 g (11.3 mmoles) of 20-(1,3-dioxolan-2-yl)pregna-1,4,6-trien-3-one was used in lieu of 4.66 g of 20-(5,5-dimethyl-1,3-dioxan-2-yl)pregna-1,4,6-trien-3-one to give 3.25 g of 20-(1,3-dioxolan-2-yl)-1α,2α-epoxypregna-4,6-dien-3-one (yield: 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05359055 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-c267d7c12ce34bed8bd23eaa06dc5751 |
| Source note | uspto-grants-1994_10 |