HuagongsheHuagongshe Chemistry Print Report · For research reference only
21,21-Dimethoxy-20-methylpregna-5,7-diene-1alpha,3betadiol → 1alpha,3beta-Dihydroxypregna-5,7-diene-20-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 21,21-Dimethoxy-20-methylpregna-5,7-diene-1alpha,3betadiol | HCID 57189343 | — |
| Reactant | 20-(5,5-Dimethyl-1,3-dioxan-2-yl)pregna-5,7-diene-1alpha,3beta-diol | HCID 67852945 | — |
| Product | 1alpha,3beta-Dihydroxypregna-5,7-diene-20-carbaldehyde | HCID 53892781 | 78.3% |
Reaction Steps
The procedure of Example 25 was repeated except that 2.6 mg (0.00667 mmole) of 21,21-dimethoxy-20-methylpregna-5,7-diene-1α,3β-diol was used in lieu of 4.3 mg of 20-(5,5-dimethyl-1,3-dioxan-2-yl)pregna-5,7-diene-1α,3β-diol to give 1.8 mg of 1α,3β-dihydroxypregna-5,7-diene-20-carbaldehyde (yield: 78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05359055 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-99ba9c9c0b684eefafe861686fd1b3b9 |
| Source note | uspto-grants-1994_10 |