HuagongsheHuagongshe Chemistry Print Report · For research reference only
1alpha,3beta-Bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde → 20-(5,5-Dimethyl-1,3-dioxan-2-yl)-1alpha-(methoxycarbonyl)oxypregna-5,7-dien-3beta-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1alpha,3beta-Bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde | HCID 54367523 | — |
| Reactant | 20-(5,5-Dimethyl-1,3-dioxan-2-yl)-1alpha,3beta-bis(methoxycarbonyloxy)pregn-5,7-diene | HCID 67852971 | — |
| Product | 20-(5,5-Dimethyl-1,3-dioxan-2-yl)-1alpha-(methoxycarbonyl)oxypregna-5,7-dien-3beta-ol | HCID 67852917 | 95.1% |
Reaction Steps
The reaction and workup procedures of Example 164 were repeated except that 100 mg of 20-(5,5-dimethyl-1,3-dioxan-2-yl)-1α,3β-bis(methoxycarbonyloxy)pregna-5,7-diene was used in lieu of 100 mg of 1α,3β-bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde to give 85 mg of 20-(5,5-dimethyl-1,3-dioxan-2-yl)-1α-(methoxycarbonyl)oxypregna-5,7-dien-3β-ol showing the following physical properties.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05359055 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-101eccd6095c44bfa8dc448a36ebc9d0 |
| Source note | uspto-grants-1994_10 |