HCID 67830815, compound → HCID 11400846, compound

HRID 1708876Notes

Reaction equation

HRID 1708876 reaction equation
C(OC([N:11]1[CH2:14][C@H:13]([C:15]([OH:17])=[O:16])[C@@H:12]1[C:18]([OH:20])=[O:19])=O)C1C=CC=CC=1.[H][H]>[Pd].CO>[NH:11]1[CH2:14][C@H:13]([C:15]([OH:17])=[O:16])[C@@H:12]1[C:18]([OH:20])=[O:19]

Participants

5

Reactant 2

HCID 67830815HCID 67830815, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 11400846HCID 11400846, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

cis-N-(Benzyloxycarbonyl) azetidine-2,3-dicarboxylic acid, 10% Pd/C and methanol are hydrogenated under 3 atm of hydrogen in a Parr shaker for 4 hours. The catalyst is filtered off and thoroughly washed. The solution is evaporated to dryness and dried in vacuo to arrive at cis-azetidine2,3-dicarboxylic acid.

Workup

  1. filtrationThe catalyst is filtered off
  2. washthoroughly washed
  3. customThe solution is evaporated to dryness
  4. customdried in vacuo

Sources & evidence

ORD record
ord-bc62cf4cd6e242fa93fda1c07f364061
Source dataset
uspto-grants-1990_08
Patent number
US04946839

Reaction notes

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