Androsta-5,7-diene-3b,17b-diol → 5alpha-Androst-7-ene-3-one-17beta-ol

HRID 1708903Notes

Reaction equation

HRID 1708903 reaction equation
[CH3:1][C@:2]12[CH2:19][CH2:18][C@H:17]3[C:7](=[CH:8][CH:9]=[C:10]4[C@:15]3([CH3:16])[CH2:14][CH2:13][C@H:12]([OH:20])[CH2:11]4)[C@@H:6]1[CH2:5][CH2:4][C@@H:3]2[OH:21].O=C1CC[C@@]2(C)C(CC[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3CC[C@@H]2CO)=C1>>[CH3:1][C@:2]12[CH2:19][CH2:18][C@H:17]3[C:7](=[CH:8][CH2:9][C@@H:10]4[C@:15]3([CH3:16])[CH2:14][CH2:13][C:12](=[O:20])[CH2:11]4)[C@@H:6]1[CH2:5][CH2:4][C@@H:3]2[OH:21]

Participants

3

Reactant 2

HCID 9817420Androsta-5,7-diene-3b,17b-diolHCID 1437761717beta-Hydroxymethyl-4-androsten-3-on

Product 1

HCID 186380785alpha-Androst-7-ene-3-one-17beta-ol

Procedure

The title compound is prepared according to the procedure of Example 4 (i) by substituting androst-4,7-diene-3,17-dione for 3-oxo-17β-(hydroxymethyl)-4androstene.

Sources & evidence

ORD record
ord-87d4d913ed0d484e81718978f900151b
Source dataset
uspto-grants-1990_08
Patent number
US04946834

Reaction notes

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