HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → HCID 178470518, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | Ethyl cyanoformate | HCID 69336 | — |
| Reactant | HCID 178524966 | HCID 178524966 | — |
| Product | HCID 178470518 | HCID 178470518 | — |
Reaction Steps
Tetrazole-5-carboxylic acid can be prepared by treating ethyl cyanoformate with sodium azide and ammonium chloride to form ethyl tetrazole-5-carboxylate, which is hydrolyzed with alkali (e.g., KOH) to give alkali tetrazole-5-carboxylate, according to the method described in J. Med. Chem. 19, 289(1976) and Ibid, 29, 538(1986).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04946855 |
| Source dataset | uspto-grants-1990_08 |
| ORD ID | ord-d2c23e0435024c3188929fa249e85593 |
| Source note | uspto-grants-1990_08 |