Glycerol → 113-92-8

HRID 1708996Notes

Reaction equation

HRID 1708996 reaction equation
[CH3:1][N:2]([CH2:4][CH2:5][CH:6]([C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][N:19]=1)[C:7]1[CH:8]=[CH:9][C:10]([Cl:13])=[CH:11][CH:12]=1)[CH3:3].[CH:20](/[C:25]([OH:27])=[O:26])=[CH:21]/[C:22]([OH:24])=[O:23].O[CH2:29][CH:30]([CH2:32][OH:33])O>>[N:2]1([C:22]([O-:24])=[O:23])[CH2:1][CH2:29][CH2:30][C:32]1=[O:33].[CH3:1][N:2]([CH2:4][CH2:5][CH:6]([C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][N:19]=1)[C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][CH:8]=1)[CH3:3].[CH:20](/[C:25]([OH:27])=[O:26])=[CH:21]/[C:22]([OH:24])=[O:23]

Participants

4

Reactant 2

HCID 753GlycerolHCID 5281068113-92-8

Product 2

HCID 5281068113-92-8Yield 0.25%HCID 21917698Pyrrolidone carboxylate

Procedure

0.025 g of chlorpheniramine maleate are dissolved in 0.05 g of glycerine and 9.925 g of 1.5% aqueous chitosonium pyrrolidone carboxylate, giving a clear, colorless solution (0.25% chlorpheniramine maleate). This lotion is useful in the treatment of rashes and inflammation due to allergic reactions.

Sources & evidence

ORD record
ord-9539f0bebf7b4b2da4023f36eb075703
Source dataset
uspto-grants-1990_08
Patent number
US04946870

Reaction notes

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