L-Aspartic Acid → N-[(3S)-Tetrahydro-2,5-dioxo-3-furanyl]formamide

HRID 1709043Notes

Reaction equation

HRID 1709043 reaction equation

[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=O.[C:10](OC(=O)C)(=[O:12])C>C(O)=O>[CH:10]([NH:1][C@@H:2]1[C:7](=[O:8])[O:9][C:4](=[O:6])[CH2:3]1)=[O:12]

Participants

4

Reactant 2

HCID 5960L-Aspartic Acid

HCID 7918Acetic Anhydride

Product 1

HCID 11298025N-[(3S)-Tetrahydro-2,5-dioxo-3-furanyl]formamide

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

formylating L-aspartic acid in a reaction mixture of formic acid and acetic anhydride to yield N-formyl-L-aspartic anhydride;

Sources & evidence

ORD record: ord-570a30861a934e68a9d4c80ecc9da2a0
Source dataset: uspto-grants-1990_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04946988

Reaction notes

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