Diethyl Malonate → Diethyl-4-[4'-(4""-trifluoromethyl-phenoxy)-phenoxy]-2-pentenoyl-malonate

Participants

Reaction Steps

One proceeds in an analogous manner to the process disclosed in Example 4 by reacting 4-[4'-(4"-trifluoromethyl-phenoxy)-phenoxy]-2-pentenoic acid at first with 12 g of pivaloyl chloride and thereafter with diethyl-ethoxy-magnesium malonate prepared from 17.6 g of diethyl malonate. The reaction mixture is worked up. 43 g of of the viscous oily desired compound are obtained which turns to a faint yellow crystalline product on standing. Mp.: 52°-55° C., yield 87%.

Provenance & Evidence