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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1709117Generated: November 1, 2026

Phthalic Anhydride → N-(7-chloro-2,3-dihydro-2-(hydroxymethyl)-4-benzofuranyl)phthalimide

https://huagongshe.com/reaction/1709117

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhthalic AnhydrideHCID 6811—
Reactant4-Chloro-3-[(prop-2-en-1-yl)oxy]anilineHCID 54496113—
ReactantN-(2-allyl-4-chloro-3-hydroxyphenyl)-3,4,5,6-tetrahydrophthalimideHCID 57171405—
ProductN-(7-chloro-2,3-dihydro-2-(hydroxymethyl)-4-benzofuranyl)phthalimideHCID 15018907—

Reaction Steps

The title compound was prepared, as a white solid, m.p.: 181°-183° C., from 3B and phthalic anhydride in three steps, according to the procedures described for preparing Example 4 from 3D.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04948418
Source datasetuspto-grants-1990_08
ORD IDord-64c6a1b5df95449d825c9dcbbba92384
Source noteuspto-grants-1990_08