1-Bromo-2-methylpropane → HCID 54061097, compound

Participants

Reaction Steps

The Grignard reagent obtained by reacting 11.8 g (0.49 g-atoms) of magnesium in 50 ml of ether with 67.13 g (0.49 mol) of isobutyl bromide in 250 ml of ether is reacted with 40.0 g (0.41 mol) of 2-methyl-2-pentenal in 100 ml of ether. The fractional distillation of the crude product (94 g) over a 20 cm Widmer column gives 44.4 g (69.4%) of olfactorily good 4,7-dimethyl-3-octen-5-ol of boiling point 47°-48° C./0.04 Torr.

Provenance & Evidence