2-Bromobutane → HCID 54408568, compound

Participants

Reaction Steps

The Grignard reagent obtained by reacting 18.7 g (0.77 g-atom) of magnesium in 100 ml of ether with 105.4 g (0.77 mol) of 2-bromobutane in 300 ml of ether is reacted with 62.72 g (0.64 mol) of 2-methyl-2-pentenal in 200 ml of ether. The fractional distillation of the crude product (98.8 g) over a 20 cm Widmer column gives 68.4 g (68.5%) of olfactorily good 4,6-dimethyl-3-octen-5-ol of boiling point 83° C./12 Torr.

Provenance & Evidence