Potassium Nitrate → HCID 19827792, compound

HRID 1709203Notes

Reaction equation

HRID 1709203 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([NH:7][C:8](=[O:15])[C:9](=[O:14])[N:10]2[CH3:13])=[CH:5][CH:4]=1.[N+:16]([O-])([O-:18])=[O:17].[K+]>S(=O)(=O)(O)O>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([NH:7][C:8](=[O:15])[C:9](=[O:14])[N:10]2[CH3:13])=[CH:5][C:4]=1[N+:16]([O-:18])=[O:17]

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 13437023HCID 13437023, compound

Product 1

HCID 19827792HCID 19827792, compoundYield 84.6%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

To a solution of 0.5 g (2.4 mmol) 7-methoxy-1-methylquinox-aline-2,3(1H,4H)-dione in 20 ml concentrated sulfuric acid was added at 0° C. 0.25 g (2.48 mmol) potassium nitrate. Stirring was continued at 0° C. for 30 min, and then at 25° C. for 90 min. The reaction mixture was poured into 100 ml icewater to give 0.51 g (84%) of 7-methoxy-1-methyl-6-nitroquinoxaline- 2,3(1H,4H)-dione as a precipitate. M.p. 343° C. NMR (DMSO-d6): 11.9 (1H, broad s), 7.67 (1H, s), 7.0 (1H, s), 3.97 (3H, s), 3.53 (3H, s).

Workup

  1. waitat 25° C. for 90 min
  2. additionThe reaction mixture was poured into 100 ml icewater

Sources & evidence

ORD record
ord-7a29f16769ac404eae68047d4dc758f2
Source dataset
uspto-grants-1990_08
Patent number
US04948794

Reaction notes

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