참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 2-(2,3-Dioxo-1,2,3,4-tetrahydroquinoxalin-1-yl)acetic acid | HCID 12938664 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-methoxycarbonylmethylquinoxaline-2,3(1H,4H)-dione | HCID 12938665 | 21% |
반응 단계
A mixture of 1.0 g (4,5 mmol) 1-carboxymethylquinoxaline-2,3(1H,4H)-dione, 15 ml dry methanol and 0,2 ml concentrated sulfuric acid was stirred at 80° C. for 1 h. After cooling to 25° C. the reaction mixture was poured in water and made alkaline. The precipitate was filtered off and recrystallized (acetone) to give 0.22 g (21%) 1-methoxycarbonylmethylquinoxaline-2,3(1H,4H)-dione. M.p. 269° C. 1H-NMR (DMSO-d6 ): 12.0 (1H, broad s), 7.1 (4H, s), 4.9 (2H, s), 3.7 (3H, s).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04948794 |
|---|
| 출처 데이터셋 | uspto-grants-1990_08 |
|---|
| ORD ID | ord-4639ed60cc8e4cc09cbec31fc2d78fbb |
|---|
| 출처 메모 | uspto-grants-1990_08 |
|---|
