HCID 19808452, compound → HCID 19990411, compound

Participants

Reaction Steps

A solution of 2 g (7.3 mmol) 4-chloro-2-ethoxalylamino-1nitrobenzene in 50 ml dimethyIformamide was hydrogenated at atm. pressure by using Ra-Ni (0.2 g) as a catalyst. The reaction mixture was filtered and evaporated in vacuo. The residue was stirred with water to give a crude product. Recrystallization (dimethylformamide-water) gave 1.2 g (78%) 6-chloro-1-hydroxyquinoxaline-2,3(1H,4H)-dione M.p. >300° C. 1H-NMR (DMSO-d6): 11.8 (2H, broad s), 7.2 (3H, m). MS (m/e): 212 (M+, 60%).

Provenance & Evidence