Water → HCID 14835664, compound

Participants

Reaction Steps

4.46 g of 7-methyl-10,11-dihydro-5H-benzo-[4,5]cyclohepta[1,2-b]pyridin-5-one was dissolved in 22 ml of ethanol. To the solution was added 0.39 g of sodium borohydride with water-cooling. The resulting mixture was stirred for 1 hour at room temperature. To the reaction mixture was added 44 ml of water. The resulting crystals were collected by filtration and dried to obtain 4.19 g of 5-hydroxy-7-methyl-10,11-dihydro-5H-benzo[4,5]cyclohepta[1,2-b]pyridine. They were recrystallized from ethanol to obtain 3.90 g of colorless crystals having a melting point of 202°-203° C.

Provenance & Evidence