HCID 13826056, compound → HCID 13826038, compound

Participants

Reaction Steps

Into a solution of 12.8 g. (59.4 mmole) pyridinium chlorochromate and 250 ml. methylene chloride are introduced, with stirring at ambient temperature, 14.0 g. (39.6 mmole) 4-chlorobenzenesulphonic acid-[4-(3-hydroxypropyl)-phenethylamide]. The reaction mixture is stirred for a further hour and then poured off from insolubles. The methylene chloride phase is chromatographed with a short column (silica gel/methylene chloride) and evaporated. Yield 10.8 g. (78% of theory); m.p. 65°-66° C. Oxime: m.p. 156°-158° C. (recrystallised from toluene).

Provenance & Evidence