1-(Triphenylphosphoranylidene)acetone → HCID 70373258, compound

Participants

Reaction Steps

A mixture of 3.2 g. (10 mnole) 4-chlorobenzenesulphonic acid-(4-formylphenethylamide), 50 ml. anhydrous toluene and 3.2 g. (10 mmole) 1-triphenylphosphoranylidene-2-propanone is refluxed for 5 hours, then cooled, stirred with silica gel and filtered off with suction. The filtrate is evaporated and purified by column chromatography (silica gel/methylene chloride). Yield 1.3 g. (36% of theory); m.p. 111°-113° C.

Provenance & Evidence