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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1709304Generated: October 31, 2026

1-Methylpiperazine → HCID 14608784, compound

https://huagongshe.com/reaction/1709304

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
ReactantHCID 14608782HCID 14608782—
ProductHCID 14608784HCID 1460878479.1%

Reaction Conditions

Temperature110 °C

Reaction Steps

A mixture of 2.0 g of ethyl 8,9-difluoro-6-oxo-6H-benzo[c]quinolizine-5-carboxylate and 3.3 g of N-methylpiperazine was heated at 110° C. for 2 hours. The solvent was evaporated and the residue partitioned between water and dichloromethane. The organic layer was dried and the solvent removed giving 2.0 g of the desired product, mp 167°-170° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04948894
Source datasetuspto-grants-1990_08
ORD IDord-5e015ef041b94a709ef05b8ae492cbe8
Source noteuspto-grants-1990_08