Hydrochloric Acid → HCID 178474704, compound

Participants

Reaction Steps

0.6 Gram of 2-acetyl-5-[2-(4-methylphenylthio)ethyl]cyclohexane-1,3-dione was dissolved in 60 ml of ethanol, and after adding 0.25 g of ethoxyamine hydrochloride and 0.26 g of triethylamine, the resulting solution was stirred overnight at room temperature. The reaction solution was poured into water, acidified with dilute hydrochloric acid and extracted with chloroform. After removing chloroform, the product obtained was purified by thin layer chromatography (developing solvent, hexane:ethyl acetate=3:1) to obtain 0.4 g of 2-(1-ethoxyaminoethylidene)-5-[2-(4-methylphenylthio)ethyl]cyclohexane-1,3-dione [Compound (2)].

Provenance & Evidence