HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 6-Oxohexanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Methyl 6-oxohexanoate | HCID 81164 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-Oxohexanoic acid | HCID 440918 | 57% |
Reaction Steps
36 g of methyl 5-formylvalerate, 90 g of water and 0.5 g of sulfuric acid were heated under reflux for 3.5 hours, the methanol formed being distilled off continuously. Fractional vacuum distillation gave 18.5 g of 5-formylvaleric acid (yield 57% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04950429 |
| Source dataset | uspto-grants-1990_08 |
| ORD ID | ord-453ca0aaeee1497da2a97db3be4c42e4 |
| Source note | uspto-grants-1990_08 |