Sodium Hydroxide → HCID 14879929, compound

Participants

Reaction Steps

A mixture of 2-[(4-phenyl)benzyl]-2-propenyl chloride (4 g.), formed in a manner analogous to that used in Example 1, and 4-methylpiperidine (3.3 g.) in p-xylene (15 ml.) was refluxed for five hours, cooled and neutralized with 25% aqueous sodium hydroxide (15 ml.). The mixture was extracted with toluene, dried over sodium sulfate and evaporated under reduced pressure to give an oil. The oil was distilled under vacuum and the fraction boiling at 195° C. to 200° C. at a pressure of 0.7 mm Hg. was collected and identified as 1-[2-[(4-phenyl)benzyl]-2-propenyl]-4-methylpiperidine. The compound, obtained in a yield of 3.5 g., solidified after being left at room temperature for a few hours. The solid was characterized by a melting point of 53° C.

Provenance & Evidence