HCID 23036513, compound → HCID 23036529, compound

Participants

Reaction Steps

100 mg of intramolecularly deprotonized 2-[[(2-chloro-2-methylpropyl)thio]methyl]-4-methoxy-3-methyl-1-[5-(trifluoromethyl)-2-benzimidazolyl]pyridinium cation were dissolved in 5 ml of ethyl acetate, whereupon 0.5 ml of 4.7N methanolic hydrochloric acid was added, the solution was concentrated and the residue was crystallized from tert.-butyl methyl ether/ether. The 2-[[(2-chloro-2-methylpropyl)thio]methyl]-4-methoxy-3-methyl-1-[5-(trifluoromethyl)-2-benzimidazolyl]pyridinium chloride obtained exhibited a melting point of 140°-142° (decomposition).

Provenance & Evidence