Methanesulfonic Acid → HCID 23036496, compound

Participants

Reaction Steps

450 mg of intramolecularly deprotonized 2-[((2-ethoxy-2-methylpropyl)thio]methyl]-4-methoxy-3-methyl-1-[5-(trifluoromethyl)-2-benzimidazolyl]pyridinium cation were dissolved in methanol and treated with 110 mg of methanesulfonic acid. The solution was concentrated several times while adding n-hexane each time. The residue was crystallized from tert. butyl methyl ether. The 2-[[(2-ethoxy-2-methylpropyl)thio]methyl]-4-methoxy-3-methyl-1-[5-(trifluoromethyl)-2-benzimidazolyl]pyridinium methanesulfonate obtained exhibited a melting point of 49°-54°.

Provenance & Evidence