Potassium Iodide → HCID 23036271, compound

HRID 1709901Notes

Reaction equation

HRID 1709901 reaction equation
C(O)(=O)C(O)=[O:3].[C:7]1([C:13]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)=[C:14]2[CH2:19][CH2:18][N:17]([CH2:20][CH2:21][CH2:22][O:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH2:16][CH2:15]2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.C1(C(C2C=CC=CC=2)(C2CCNCC2)O)C=CC=CC=1.BrCCCOC1C=CC=CC=1.C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>C(O)CCC>[O:23]([CH2:22][CH2:21][CH2:20][N:17]1[CH2:16][CH2:15][CH:14]([C:13]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)([C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=2)[OH:3])[CH2:19][CH2:18]1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

7

Reactant 5

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 15723AzacyclonolHCID 68522Benzene, (3-bromopropoxy)-HCID 230363354-(Diphenylmethylene)-1-(3-phenoxypropyl)piperidine oxalate

Product 1

HCID 23036271HCID 23036271, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

This compound was prepared according to the procedure used to synthesize the compound of Example 1. A mixture of 4.0 g (0.015 mole) of α, α-diphenyl-4-piperidinemethanol, 3.2 g (0.015 mole) of 1-bromo-3-phenoxypropane, 5.3 g (0.05 mole) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 100 ml of 1-butanol gave 3.2 g (53%) of title compound as a white solid, mp 87°-88° C.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-79ed7ed5b4e6494295f0347fa78796c7
Source dataset
uspto-grants-1990_08
Patent number
US04950674

Reaction notes

Loading…