Oxalic Acid → HCID 23036440, compound

Participants

Reaction Steps

This compound was prepared according to the procedure used to synthesize the compound of Example 1. A mixture of 4.6 g (0.015 mole) of α, α-bis(4-methylphenyl)-4-piperidinemethanol, 3.6 g (0.015 mole) of 1-[4-(3-chloropropoxy)-3-methoxyphenyl]ethanone, 5.3 g (0.05 mole) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 100 ml of 1-butanol gave a brown gum as residue. The gum was converted to the oxalic acid salt and the solid was recrystallized from absolute ethanol to yield 5.3 g (58%) of title compound as an off-white solid, mp 92°-95° C. with decomposition.

Provenance & Evidence