Phenyl chloroformate → HCID 178521792, compound

Participants

Reaction Steps

250 ml of N,N-dimethylacetoamide was added to a mixture of 36.6 g of 5-amino-2-mercaptobenzoimidazole with 7.1 ml of pyridine, and 34.4 g phenyl chloroformate was then added dropwisely to the obtained mixture at room temperature. After the obtained mixture had been agitated at room temperature for 1.5 hours, the mixture was poured into 1.5 1 of ice water to separate crystals. The obtained crystals were filtered off and then recrysyallized from acetonitrile, to obtain 47.7 g of 2-mercapto-5-phenoxycarbonylaminobenzoimidazole.

Provenance & Evidence