6,11-Dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol--hydrogen chloride (1/1) → 6-Chloro-5-cyclohexyl-2,3-dihydro-1H-indene-1-carboxylic acid

HRID 1709967Notes

Reaction equation

HRID 1709967 reaction equation
CC(N1CCC(CC2C=CC=[CH:23][CH:24]=2)CC1)C(O)C1C=CC(O)=CC=1.[C:25]([O-:34])(=[O:33])[CH:26]([CH:28]([C:30]([O-])=O)O)O.[ClH:35].O[C:37]1[CH:48]=[CH:47][C:46]2C[CH:44]3N(C[CH2:56][C:40]([CH:42]3C)(C)[C:39]=2[CH:38]=1)CC=C(C)C>>[CH:56]1[C:30]2[CH2:24][CH2:23][CH:26]([C:25]([OH:34])=[O:33])[C:28]=2[CH:44]=[C:42]([Cl:35])[C:40]=1[CH:39]1[CH2:38][CH2:37][CH2:48][CH2:47][CH2:46]1

Participants

3

Reactant 2

HCID 1977586,11-Dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol--hydrogen chloride (1/1)HCID 86744177HCID 86744177, compound

Product 1

HCID 1201086-Chloro-5-cyclohexyl-2,3-dihydro-1H-indene-1-carboxylic acid

Procedure

Example 25: 1 g of ifenprodil tartarate; Example 29: 1 g of pentazocine hydrochloride.

Sources & evidence

ORD record
ord-b8a1b5f7ab71462ea53f75083dd9dc48
Source dataset
uspto-grants-1990_08
Patent number
US04952560

Reaction notes

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