Water → HCID 23035243, compound

Participants

Reaction Steps

A mixture of 4,5-dihydro-6-(5,6-dihydroxy-benzo[b]thien-2-yl)-5-methyl-3(2H)-pyridazinone (1.59 g) and anhydrous potassium carbonate (1.69 g) in dimethyl formamide (18 ml) was stirred at room temperature for 10 mins. Iodoethane (0.92 ml) was then added and the reaction mixture was stirred for 16 hours. The resultant suspension was then poured into water (90 ml), the mixture was stirred, and the light yellow coloured precipitate was filtered off and dried at 75° C. under vacuum to give 4,5-dihydro-6-(5,6-diethoxy-benzo[b]thien-2-yl)-5-methyl-3(2H)-pyridazinone (1.65 g). Crystallization from dichloromethane: methanol and diethyl ether gave 4,5-dihydro-6-(5,6-diethoxybenzo[b]thien-2-yl)-5-methyl-3(2H)-pyridazinone as a white solid (1.38 g), m.p. 170°-171° C.

Provenance & Evidence