4-Chloro-3,5-dinitrobenzonitrile → 4-Fluoro-3,5-dinitrobenzonitrile

Participants

Reaction Conditions

Reaction Steps

A mixture of 7.0 parts of anhydrous potassium fluoride and 5.0 parts of 4-chloro-3,5-dinitrobenzonitrile was heated and maintained at about 150° C., with stirring, for a period of about 6 hours, under a positive pressure of nitrogen. The reaction mixture, a viscous, dark brown liquid was filtered and washed with methylene chloride. Analysis of the filtrate by gas chromatographic techniques indicated a 69% conversion and a 5% yield of 4-fluoro-3,5-dinitrobenzonitrile.

Provenance & Evidence