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HRID1710244

反应详情

EQUATION

反应方程式

HRID 1710244 的结构方程式

REACTANTS

反应物

1
结构：CO[C@H]1C(=O)N(C(=O)C(=O)OCC(Cl)(Cl)Cl)[C@@H]1SC(C)=O
HCID86741783

未命名化合物

PRODUCTS

生成物

1
结构：CO[C@H]1C(=O)N[C@@H]1SC(C)=O
HCID56630779

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

3
结构：CO
溶剂HCID887

Methanol

CH4O

结构：O
溶剂HCID962

Water

H2O

结构：COC(C)=O
溶剂HCID6584

Methyl acetate

C3H6O2

PROCEDURE

实验过程

A solution of 1.52 g of 2-[(3S,4R)-4-acetylthio-3-methoxy-2-oxoazetidin-1-yl]-2-oxoacetic acid 2,2,2-trichloroethyl ester (crude product) in 290 ml of methanol, 40 ml of methyl acetate and 5.9 ml of water is refluxed for 20 minutes under nitrogen. The solvent is evaporated off in vacuo. After chromatography over silica gel with toluene/ethyl acetate (3:1) the residue yields the title compound.

WORKUP

后处理

  1. customThe solvent is evaporated off in vacuo