2,5-Dimethylpyrrolidine → HCID 25205006, compound

HRID 1710346Notes

Reaction equation

HRID 1710346 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:18]=1Cl)=[O:13])[CH2:8]2.[CH3:26][CH:27]1[CH2:31][CH2:30][CH:29]([CH3:32])[NH:28]1>>[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:18]=1[N:28]1[CH:29]([CH3:32])[CH2:30][CH2:31][CH:27]1[CH3:26])=[O:13])[CH2:8]2

Participants

3

Reactant 2

HCID 960342,5-DimethylpyrrolidineHCID 575502625-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide2×

Product 1

HCID 25205006HCID 25205006, compound

Procedure

5-(2,5-Dimethyl-pyrrolidin-1-y1)-1-phenyl-1H-pyrazole-4-carboxylic acid adamant-2-ylamide was prepared using Procedure A from 5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide (Intermediate 3) and 2,5-dimethylpyrrolidine. Mass spectrum (ES) MH+=419.

Sources & evidence

ORD record
ord-3f8bf55028704b888f1dcd495120b544
Source dataset
uspto-grants-2010_09
Patent number
US07790711B2

Reaction notes

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