Piperidin-3-ylmethanol → HCID 25204050, compound

HRID 1710354Notes

Reaction equation

HRID 1710354 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:18]=1Cl)=[O:13])[CH2:8]2.[NH:26]1[CH2:31][CH2:30][CH2:29][CH:28]([CH2:32][OH:33])[CH2:27]1>>[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][C:12]([C:14]1[CH:15]=[N:16][N:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:18]=1[N:26]1[CH2:31][CH2:30][CH2:29][CH:28]([CH2:32][OH:33])[CH2:27]1)=[O:13])[CH2:8]2

Participants

3

Reactant 2

HCID 107308Piperidin-3-ylmethanolHCID 575502625-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide2×

Product 1

HCID 25204050HCID 25204050, compound

Procedure

5-(3-Hydroxymethyl-piperidin-1-y1)-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide was prepared using Procedure A from 5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide (Intermediate 3) and 3-piperidinemethanol. Mass spectrum (ES) MH+=435.

Sources & evidence

ORD record
ord-bff61e3e7943451280be5ad56cc78ef1
Source dataset
uspto-grants-2010_09
Patent number
US07790711B2

Reaction notes

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