Piperidine → Piperidine, 1-(1-cyclopenten-1-yl)-

Participants

Reaction Conditions

Reaction Steps

Piperidine (4.0 g, 46.98 mmol) was added to a solution of cyclopentanone Compound 1a (4.0 g, 46.50 mmol) in benzene (100 mL) at ambient temperature under a N2 atmosphere. The mixture was refluxed at 80° C. for 5 hrs using a Dean Stark apparatus, then concentrated to dryness to provide 1-cyclopent-1-enyl-piperidine Compound 1b (7.0 g) as a crude oil which was used in the next step without further purification.

Provenance & Evidence