HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tert-butyl 4-(5-amino-2-methoxyphenyl)piperazine-1-carboxylate → 3-Difluoromethoxy-4-methoxy-N-(4-methoxy-3-piperazin-1-yl-phenyl)-benzenesulfonamide Hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tert-butyl 4-(5-amino-2-methoxyphenyl)piperazine-1-carboxylate | HCID 10686178 | — |
| Edukt | 3-(Difluoromethoxy)-4-methoxybenzenesulfonyl chloride | HCID 45133081 | — |
| Produkt | 3-Difluoromethoxy-4-methoxy-N-(4-methoxy-3-piperazin-1-yl-phenyl)-benzenesulfonamide Hydrochloride | HCID 67094616 | — |
Reaktionsschritte
The compound was prepared as described for Example 1 by reaction of 4-(5-amino-2-methoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester and commercially available 3-difluoromethoxy-4-methoxy benzene sulfonylchloride, followed by deprotection under acidic conditions.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07790727B2 |
| Quelldatensatz | uspto-grants-2010_09 |
| ORD ID | ord-d78e1f5ae63449148a4ccdfb71b40d15 |
| Quellennotiz | uspto-grants-2010_09 |