HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → 3-Difluoromethoxy-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-N-methyl-benzenesulfonamide Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 3-Difluoromethoxy-N-(4-methoxy-3-piperazin-1-yl-phenyl)-N-methyl-benzene-sulfonamide Hydrochloride | HCID 67094860 | — |
| Product | 3-Difluoromethoxy-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-N-methyl-benzenesulfonamide Hydrochloride | HCID 67094824 | — |
Reaction Steps
The compound was prepared by reaction of 3-difluoromethoxy-N-[4-methoxy-3-(piperazin-1-yl)-phenyl]-N-methyl-benzenesulfonamide hydrochloride (compound of example 2) with aqueous formaldehyde and sodium triacetoxyborohydride as described for example 5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07790727B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-bf7309fc435b4f5ab4095b0dd9e29636 |
| Source note | uspto-grants-2010_09 |