HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1710672Generated: November 1, 2026
Acetic Acid → 3-(3-Chloro-2-methyl-phenyl)-imidazolidin-4-one
https://huagongshe.com/reaction/1710672
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 2-amino-N-(3-chloro-2-methylphenyl)acetamide | HCID 2517697 | — |
| Product | 3-(3-Chloro-2-methyl-phenyl)-imidazolidin-4-one | HCID 59434031 | — |
Reaction Steps
A mixture of 2-amino-N-(3-chloro-2-methyl-phenyl)-acetamide (74) (1.18 g, 1 equiv), paraformaldehyde (HCHO)n (0.77 g, 1.5 equiv) and 3 mL of acetic acid was heated at 90° C. for 3 h and evaporated to dryness to afford 3-(3-chloro-2-methyl-phenyl)-imidazolidin-4-one (75) as acetic acid salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07790726B2 |
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| Source dataset | uspto-grants-2010_09 |
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| ORD ID | ord-cbd1f025f45747c5a5357cd360964bc1 |
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| Source note | uspto-grants-2010_09 |
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