HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Chloro-4-nitrophenol → 4-(3-Chloro-4-nitrophenoxy)thieno[3,2-d]pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Chloro-4-nitrophenol | HCID 10283 | — |
| Edukt | 4-Chlorothieno[3,2-d]pyrimidine | HCID 2735821 | — |
| Edukt | 4-(2-Fluoro-4-nitrophenoxy)-N-(2-morpholinoethyl)thieno[3,2-d]pyrimidine-6-carboxamide | HCID 59424553 | — |
| Produkt | 4-(3-Chloro-4-nitrophenoxy)thieno[3,2-d]pyrimidine | HCID 47446362 | 72% |
Reaktionsschritte
Starting from the chloride 20 (scheme 4) and following the procedure described above for the synthesis of compound 24 (scheme 4, example 22) replacing 2-fluoro-4-nitrophenol with 3-chloro-4-nitrophenol, title compound 171 was obtained in 72% yield. LRMS (M+1) 307.7 (100%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07790729B2 |
| Quelldatensatz | uspto-grants-2010_09 |
| ORD ID | ord-5d7aff047d6748c78bcbac8c2df75f6d |
| Quellennotiz | uspto-grants-2010_09 |