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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1711047Generated: October 29, 2026

6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine → 4-(6-Bromothieno[3,2-b]pyridin-7-yloxy)-3-fluorobenzenamine

https://huagongshe.com/reaction/1711047

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridineHCID 59424457—
Reactant4-(1H-Pyrrolo[2,3-c]pyridin-7-yloxy)-3-fluorobenzenamineHCID 59424629—
Product4-(6-Bromothieno[3,2-b]pyridin-7-yloxy)-3-fluorobenzenamineHCID 5942467692%

Reaction Steps

Starting from the compound 272 and following the procedure described above for the synthesis of compound 261 (scheme 59, example 218, step 3), title compound 273 was obtained in 92% yield as a light brown solid. MS (m/z): 340.0 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07790729B2
Source datasetuspto-grants-2010_09
ORD IDord-9581248b01c840faa1d725020f7b24a1
Source noteuspto-grants-2010_09