Ethylamine → HCID 178464595, compound

Participants

Reaction Steps

To a solution of dimethyl cyanodithioiminocarbonate (2.85 g, 17.6 mmol) in methanol (20 mL) was added ethylamine (2M soln, 9.7 mL, 19.4 mmol). The solution was allowed to stir at reflux overnight. The solution was cooled to room temperature and the desired product crystallized out of solution over 2 hours. The crystals were collected on a buchner funnel, washed with cold methanol several times, and dried in vacuo to give 1-ethyl-2-methyl-3-cyanoisothiourea as a white solid (1.08 g, 43%). 1H NMR (CDCl3) δ 1.22 (t, 3H, J=6 Hz), 2.61 (s, 3H), 3.35 (s, 1H), 3.46 (q, 2H, J=6 Hz).

Provenance & Evidence