反应详情

5-Cyano-furan-2-carboxylic acid (2-piperidin-1-yl-phenyl)-amide (200 mg) is dissolved in a mixture of benzene (180 mL) and ethanol (20 mL). The solution is irradiated with a 100 W high pressure Hg Lamp at room temperature for 10 h, according to the method described by Kanoka and Itoh [Synthesis, 36 (1972)]. The solvent is removed in vacuo and the residue is purified by preparative thin layer chromatography (“TLC”) (silica gel) to yield the pure product.

1. customThe solution is irradiated with a 100 W high pressure Hg Lamp at room temperature for 10 h
2. customdescribed by Kanoka and Itoh [Synthesis, 36 (1972)]
3. customThe solvent is removed in vacuo
4. customthe residue is purified by preparative thin layer chromatography (“TLC”) (silica gel)
5. customto yield the pure product