1-Cyclohexenylboronic acid → HCID 58754829, compound

HRID 1711265Notes

Reaction equation

HRID 1711265 reaction equation
Br[C:2]1[C:3]([NH2:11])=[CH:4][C:5]2[O:9][CH2:8][O:7][C:6]=2[CH:10]=1.[C:12]1(B(O)O)[CH2:17][CH2:16][CH2:15][CH2:14][CH:13]=1>>[C:12]1([C:2]2[C:3]([NH2:11])=[CH:4][C:5]3[O:9][CH2:8][O:7][C:6]=3[CH:10]=2)[CH2:17][CH2:16][CH2:15][CH2:14][CH:13]=1

Participants

3

Reactant 2

HCID 38629021-Cyclohexenylboronic acidHCID 122220626-bromobenzo[d][1,3]dioxol-5-amine

Product 1

HCID 58754829HCID 58754829, compound

Procedure

The title compound was prepared by Suzuki coupling of 6-bromo-benzo[1,3]dioxol-5-ylamine (Bioorganic & Medicinal Chemistry (2002), 10(11), 3395-3400) and cyclohexen-1-ylboronic acid according the procedure Example 44, step (g). Mass spectrum (ESI, m/z): Calcd. for C13H15NO2, 218.1 (M+H), found 218.1.

Sources & evidence

ORD record
ord-badeac22e1c048038e78f6d587300c48
Source dataset
uspto-grants-2010_09
Patent number
US07790724B2

Reaction notes

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