2-(4-Nitro-phenyl)-ethanesulfonic acid tert-butylamide → 2-(4-Amino-phenyl)-ethanesulfonic acid tert-butylamide

Participants

Reaction Steps

2-(4-Nitro-phenyl)-ethanesulfonic acid tert-butylamide (as prepared in the step above, 633 mg, 2.21 mmol) was hydrogenated under balloon pressure in EtOH (20 mL) using 10% Pd/C (100 mg) for 12 h. The reaction mixture was filtered through Celite and concentrated to obtain 2-(4-amino-phenyl)-ethanesulfonic acid tert-butylamide (536 mg, 95%) which was used directly without further purification.

Provenance & Evidence